A high concept thriller that tells the Narrative of Dr. Ephraim Goodweather, the Mind of the Center for Disease Control Canary Team in Nyc. He and his team are called upon to investigate a outbreak that was mysterious using hallmarks of an early and wicked strain of vampirism. As his team, Eph, the strain spreads, and an assembly of regular New Yorkers, wage war for the fate of humankind itself.