When their car breaks down in the woods during the night, two American girls find themselves during a stop over in Germany in the center of a roadtrip through Europe. Looking at a nearby hallway, they are wooed in to the clutches of a retired surgeon that explains his vision that was crazy to his captives' absolute dread. They're still the subjects of his ailing life dream: are the first ever to connect people, one to another location, and so contribute to life"the human centipede."