U.S. national representative Leon S. Kennedy sneaks in to the"East Slavic Republic" to verify rumors that Bio-Organic Weapons (BOWs) are used in the nation's civil war, which the U.S. and Russia are making preparations to jointly intervene in. Shortly after his infiltration, the U.S. government orders him to leave instantly. Determined to uncover the facts, the order is ignored by Leon and enters the battlefield to end the chain of tragedies brought on by the BOWs.