In a world ravaged by a virus disease, turning its victims into the Undead, Alice continues on her journey to find survivors and lead them. Her battle using all the Umbrella Corporation reaches new peaks, however Alice gets some unexpected help from an older friend. A lead that maintains a safe refuge from the Undead takes them to Los Angeles, but when they arrive the town is overrun by thousands of un dead - and also even her comrades and Alice are just going to step into a deadly trap.