The Japanese armed forces slay another another huge kaiju in Yomama Bay in 1962. Prof. Hiro Honda saves her offspring, carrying the mysterious red egg away to safety in friendly Cincinnati, Ohio. However, as the jet approaches, he flushes the egg down the toilet by accident. It vanishes into the Ohio River. The egg is shortly discovered by Dr. Blowheart and his assistant, Dr. Shirley Yujest, after being shaken loose by nuclear testing. Prof. Honda soon appears and informs them that the egg contains a living Notzillasaurus Partiontilldon. He says that as long as the creature is not introduced to alcohol, it will remain little. If it is, it will multiply hundreds of times and attack the nearby city.