A fanatical animal rights activist releases giant pythons into the Everglades, presuming the wild animals should be put up. Steroids are fed by an over-zealous park ranger into wild alligators so they are able to fight back when they start decimating the native animal population. The giant pythons and alligators that are gargantuan go on a killing spree, and it's currently left up to put aside their differences to put an end into the monsters and also the destruction.