Lost in White takes places from China's northeast, where two figures are found under the ice of a frozen river, their remains made unidentifiable by fish, but bearing the mark of being dragged with a ice hook. In charge of the investigation is Captain Zhou (Tony Leung Ka Fai), a separate cop who's pulling his teenaged daughter Xinyi (Zhou Dongyu). Soon he is joined by Wang Hao (Tong Dawei) a Shanghai detective who's on a missing person case that has directed him into the very same village where the murders happened. Both cases prove to get connected: the missing person and both victims were a member of a quartet of individuals that years ago opened a refinery at the area, also discarded substance waste in an unethical way that's poisoned the waters and led to malformed babies at the following decade. Could be the businessman that is missing the killer, a red herring or another victim?