Yuuji Itadori is a boy with tremendous physical strength, though he lives a completely average high school life. One day, to conserve a pal that has been attacked by Curses, he consumes a finger of Ryoumen Sukuna, taking menstruation right into his very own spirit. After that, he shares one body with Sukuna. Guided by the most powerful of sorcerers, Satoru Gojou, Itadori is admitted to the Tokyo Prefectural Jujutsu Senior High School, a company that battles menstruations ... as well as thus begins the brave tale of a child that became a Curse to exorcise a Curse, a life from which he could never ever reverse.