The epic story of the first touch, encounter, approach, betrayal and, eventually, life-transcending friendship, between Karamakate, an Amazonian shaman, last survivor of his people, along with two scientists who, within the span of 40 decades, traveling through the Amazon looking for a sacred plant that could treat them. Inspired by the writings of the explorers of Theodor Koch-Grunberg, this Amazon and also Richard Evans Schultes.